Developing H3K27M mutant selective radiosensitization strategies in diffuse intrinsic pontine glioma

Diffuse intrinsic pontine glioma (DIPG) is a rare but highly lethal pediatric and adolescent tumor located in the pons of the brainstem. DIPGs harbor unique and specific pathological and molecular alterations, such as the hallmark lysine 27-to-methionine (H3K27M) mutation in histone H3, which lead t...

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Detalles Bibliográficos
Autores principales: Parsels, Leslie A., Wahl, Daniel R, Koschmann, Carl, Morgan, Meredith A., Zhang, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2023
Materias:
Pediatric Brain Tumor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9918797/
https://www.ncbi.nlm.nih.gov/pubmed/36724689
http://dx.doi.org/10.1016/j.neo.2023.100881

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9918797/
https://www.ncbi.nlm.nih.gov/pubmed/36724689
http://dx.doi.org/10.1016/j.neo.2023.100881

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