Cargando…

Developing H3K27M mutant selective radiosensitization strategies in diffuse intrinsic pontine glioma

Diffuse intrinsic pontine glioma (DIPG) is a rare but highly lethal pediatric and adolescent tumor located in the pons of the brainstem. DIPGs harbor unique and specific pathological and molecular alterations, such as the hallmark lysine 27-to-methionine (H3K27M) mutation in histone H3, which lead t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Parsels, Leslie A., Wahl, Daniel R, Koschmann, Carl, Morgan, Meredith A., Zhang, Qiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Neoplasia Press 2023
Materias:	Pediatric Brain Tumor
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9918797/ https://www.ncbi.nlm.nih.gov/pubmed/36724689 http://dx.doi.org/10.1016/j.neo.2023.100881

Ejemplares similares

Role of Radiation Therapy in the Management of Diffuse Intrinsic Pontine Glioma: A Systematic Review
por: Gallitto, Matthew, et al.
Publicado: (2019)

Interdisciplinary care of children with diffuse midline glioma
por: Coleman, Christina, et al.
Publicado: (2022)

The promise of metabolic imaging in diffuse midline glioma
por: Lovibond, Samantha, et al.
Publicado: (2023)

Unsupervised machine learning using K-means identifies radiomic subgroups of pediatric low-grade gliomas that correlate with key molecular markers
por: Haldar, Debanjan, et al.
Publicado: (2022)

DDRE-30. THERAPEUTIC TARGETING OF DISRUPTED METABOLIC STATE IN DIFFUSE INTRINSIC PONTINE GLIOMA
por: Mbah, Nneka, et al.
Publicado: (2021)

RARE-02. POLYAMINE PATHWAY INHIBITION IS A POTENT NOVEL THERAPEUTIC STRATEGY AGAINST DIFFUSE INTRINSIC PONTINE GLIOMA
por: Khan, Aaminah, et al.
Publicado: (2021)

RARE-08. POTENTIAL NEW THERAPIES FOR DIFFUSE INTRINSIC PONTINE GLIOMAS IDENTIFIED THROUGH HIGH THROUGHPUT DRUG SCREENING
por: Upton, Dannielle, et al.
Publicado: (2021)

Pretreatment patient-reported cognitive function in patients with diffuse glioma
por: Schei, Stine, et al.
Publicado: (2022)

Locoregional CAR T cells for children with CNS tumors: Clinical procedure and catheter safety
por: Vitanza, Nicholas A., et al.
Publicado: (2023)

Cerebrospinal Fluid biomarkers in pediatric brain tumors: A systematic review
por: Lehner, Kurt R., et al.
Publicado: (2022)

Current state of pediatric neuro-oncology imaging, challenges and future directions
por: Nabavizadeh, Ali, et al.
Publicado: (2023)

Indigenous peoples and inclusion in clinical and genomic research: Understanding the history and navigating contemporary engagement
por: Waanders, Angela, et al.
Publicado: (2023)

Why haven't we solved intracranial pediatric ependymoma? Current questions and barriers to treatment advances.
por: Hwang, Eugene I., et al.
Publicado: (2023)

Translational considerations for immunotherapy clinical trials in pediatric neuro-oncology
por: Foster, Jessica B., et al.
Publicado: (2023)

Retrospective dataset and survey analyses identify gaps in data collection for craniopharyngioma and priorities of patients and families affected by the disease
por: Marshall, Emily, et al.
Publicado: (2023)

Diffuse intrinsic pontine glioma-like tumor with EZHIP expression and molecular features of PFA ependymoma
por: Pratt, Drew, et al.
Publicado: (2020)

Diffuse intrinsic pontine glioma: poised for progress
por: Warren, Katherine E.
Publicado: (2012)

Nanotechnology Applications for Diffuse Intrinsic Pontine Glioma
por: Bredlau, Amy Lee, et al.
Publicado: (2017)

Genomic Insights into Diffuse Intrinsic Pontine Glioma
por: Lapin, Danielle H., et al.
Publicado: (2017)

DIPG-25. Patterns of cerebrospinal fluid diversion and survival in children with diffuse intrinsic pontine glioma: a report from the International Diffuse Intrinsic Pontine Glioma Registry
por: Cooney, Tabitha, et al.
Publicado: (2022)

Potent anti-tumor efficacy of palbociclib in treatment-naïve H3.3K27M-mutant diffuse intrinsic pontine glioma
por: Sun, Yu, et al.
Publicado: (2019)

Preclinical and clinical evaluation of German-sourced ONC201 for the treatment of H3K27M-mutant diffuse intrinsic pontine glioma
por: Duchatel, Ryan J, et al.
Publicado: (2021)

Targeting SWI/SNF ATPases in H3.3K27M diffuse intrinsic pontine gliomas
por: Mota, Mateus, et al.
Publicado: (2023)

Pre-Clinical Models of Diffuse Intrinsic Pontine Glioma
por: Misuraca, Katherine L., et al.
Publicado: (2015)

Epigenetic Targeted Therapy for Diffuse Intrinsic Pontine Glioma
por: HASHIZUME, Rintaro
Publicado: (2017)

Hypofractionated radiotherapy in children with diffuse intrinsic pontine glioma
por: Hayashi, Akiko, et al.
Publicado: (2020)

Immune Microenvironment and Immunotherapies for Diffuse Intrinsic Pontine Glioma
por: Chen, Yujia, et al.
Publicado: (2023)

Radiotherapy for Diffuse Intrinsic Pontine Glioma: Insufficient but Indispensable
por: Kim, Hyun Ju, et al.
Publicado: (2023)

Epigenetic and Metabolic Changes in Diffuse Intrinsic Pontine Glioma
por: Park, Jiyoon, et al.
Publicado: (2023)

Amino acid tracers in PET imaging of diffuse low-grade gliomas: a systematic review of preoperative applications
por: Näslund, Olivia, et al.
Publicado: (2018)

Repurposing Vandetanib plus Everolimus for the Treatment of ACVR1-Mutant Diffuse Intrinsic Pontine Glioma
por: Carvalho, Diana M., et al.
Publicado: (2022)

DIPG-13. TARGETING HYPOXIA AND MITOCHONDRIA WITH REPURPOSED METABOLIC DRUGS AS AN APPROACH TO RADIOSENSITIZATION FOR DIFFUSE INTRINSIC PONTINE GLIOMAS (DIPG)
por: Shen, Han, et al.
Publicado: (2020)

Multi-focal sequencing of a diffuse intrinsic pontine glioma establishes PTEN loss as an early event
por: Koschmann, Carl, et al.
Publicado: (2017)

DIPG-27. Behavioral disturbances as underestimated presenting symptoms in children with Diffuse Intrinsic Pontine Glioma (DIPG)
por: Milanaccio, Claudia, et al.
Publicado: (2022)

DIPG-27. DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG) CHALLENGE: FROM GENE EXPRESSION PROFILE TO DRUG
por: Scilimati, Antonio, et al.
Publicado: (2023)

Diffusion Tensor Histogram Analysis of Pediatric Diffuse Intrinsic Pontine Glioma
por: Steffen-Smith, Emilie A., et al.
Publicado: (2014)

SYST-07 WINDOW-OF-OPPORTUNITY STUDY OF ONC201 IN PEDIATRIC PATIENTS WITH DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG) AND THALAMIC GLIOMA
por: Odia, Yazmin, et al.
Publicado: (2022)

DIPG-62. PRECLINICAL EVALUATION OF IMIPRIDONE-BASED COMBINATION THERAPIES IN PEDIATRIC H3K27M MUTANT DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)
por: Borsuk, Robyn, et al.
Publicado: (2020)

DIPG-17. TREATMENT OF DIFFUSE INTRINSIC PONTINE GLIOMA USING ALLELE-SPECIFIC SIRNA TARGETING H3.3 K27M MUTANT HISTONE
por: Wentworth, Simon, et al.
Publicado: (2023)

Autopsy findings of previously described case of diffuse intrinsic pontine glioma-like tumor with EZHIP expression and molecular features of PFA ependymoma
por: Alturkustani, Murad, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_sadkuq3ajmg9l3bmu3q92vjpjl