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New Succinimide–Thiazolidinedione Hybrids as Multitarget Antidiabetic Agents: Design, Synthesis, Bioevaluation, and Molecular Modelling Studies

Diabetes mellitus (DM) is a metabolic disorder majorly arising from the pathophysiology of the pancreas manifested as a decline in the insulin production or the tissue’s resistance to the insulin. In this research, we have rationally designed and synthesized new succinimide–thiazolidinedione hybrids...

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Detalles Bibliográficos
Autores principales: Huneif, Mohammed A., Mahnashi, Mater H., Jan, Muhammad Saeed, Shah, Muhammad, Almedhesh, Sultan A., Alqahtani, Seham M., Alzahrani, Mohammad Jamaan, Ayaz, Muhammad, Ullah, Farhat, Rashid, Umer, Sadiq, Abdul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9918900/
https://www.ncbi.nlm.nih.gov/pubmed/36770873
http://dx.doi.org/10.3390/molecules28031207