Baicalein Induces G(2)/M Cell Cycle Arrest Associated with ROS Generation and CHK2 Activation in Highly Invasive Human Ovarian Cancer Cells

Ovarian cancer is a lethal gynecological cancer because drug resistance often results in treatment failure. The CHK2, a tumor suppressor, is considered to be an important molecular target in ovarian cancer due to its role in DNA repair. Dysfunctional CHK2 impairs DNA damage-induced checkpoints, redu...

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Detalles Bibliográficos
Autores principales: Chuang, Tzu-Chao, Shao, Wei-Syun, Hsu, Shih-Chung, Lee, Shou-Lun, Kao, Ming-Ching, Wang, Vinchi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9919047/
https://www.ncbi.nlm.nih.gov/pubmed/36770705
http://dx.doi.org/10.3390/molecules28031039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9919047/
https://www.ncbi.nlm.nih.gov/pubmed/36770705
http://dx.doi.org/10.3390/molecules28031039

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