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Development of Capillary Zone Electrophoresis Method for the Simultaneous Separation and Quantification of Metformin and Pioglitazone in Dosage Forms; and Comparison with HPLC Method

A capillary zone electrophoretic (CZE) method was developed, validated, and applied for the assay of metformin (MET) and pioglitazone (PIO) in pharmaceutical formulations. The optimum running buffer composition was found to be 75 mmol/L phosphate buffer containing 30% acetonitrile (ACN) at pH 4.0. T...

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Detalles Bibliográficos
Autores principales: AlThikrallah, Maymonah K. I., Idris, Abubakr M., Elbashir, Abdalla Ahmed, Elgorashe, Rafea E. E., Buzid, Alyah, Alnajjar, Ahmed O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9919060/
https://www.ncbi.nlm.nih.gov/pubmed/36770850
http://dx.doi.org/10.3390/molecules28031184