N-Containing α-Mangostin Analogs via Smiles Rearrangement as the Promising Cytotoxic, Antitrypanosomal, and SARS-CoV-2 Main Protease Inhibitory Agents

New N-containing xanthone analogs of α-mangostin were synthesized via one-pot Smiles rearrangement. Using cesium carbonate in the presence of 2-chloroacetamide and catalytic potassium iodide, α-mangostin (1) was subsequently transformed in three steps to provide ether 2, amide 3, and amine 4 in good...

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Detalles Bibliográficos
Autores principales: Pyae, Nan Yadanar Lin, Maiuthed, Arnatchai, Phongsopitanun, Wongsakorn, Ouengwanarat, Bongkot, Sukma, Warongrit, Srimongkolpithak, Nitipol, Pengon, Jutharat, Rattanajak, Roonglawan, Kamchonwongpaisan, Sumalee, Ei, Zin Zin, Chunhacha, Preedakorn, Wilasluck, Patcharin, Deetanya, Peerapon, Wangkanont, Kittikhun, Hengphasatporn, Kowit, Shigeta, Yasuteru, Rungrotmongkol, Thanyada, Chamni, Supakarn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9919084/
https://www.ncbi.nlm.nih.gov/pubmed/36770770
http://dx.doi.org/10.3390/molecules28031104

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9919084/
https://www.ncbi.nlm.nih.gov/pubmed/36770770
http://dx.doi.org/10.3390/molecules28031104

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