Savory Signaling: T1R Umami Receptor Modulates Endoplasmic Reticulum Calcium Store Content and Release Dynamics in Airway Epithelial Cells

T1Rs are expressed in solitary chemosensory cells of the upper airway where they detect apical glucose levels and repress bitter taste receptor Ca(2+) signaling pathways. Microbial growth leads to a decrease in apical glucose levels. T1Rs detect this change and liberate bitter taste receptor signali...

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Detalles Bibliográficos
Autores principales: McMahon, Derek B., Jolivert, Jennifer F., Kuek, Li Eon, Adappa, Nithin D., Palmer, James N., Lee, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9919336/
https://www.ncbi.nlm.nih.gov/pubmed/36771200
http://dx.doi.org/10.3390/nu15030493

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9919336/
https://www.ncbi.nlm.nih.gov/pubmed/36771200
http://dx.doi.org/10.3390/nu15030493

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