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Towards Probing Conformational States of Y2 Receptor Using Hyperpolarized (129)Xe NMR

G protein-coupled receptors can adopt many different conformational states, each of them exhibiting different restraints towards downstream signaling pathways. One promising strategy to identify and quantify this conformational landscape is to introduce a cysteine at a receptor site sensitive to dif...

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Detalles Bibliográficos
Autores principales: Schmidt, Peter, Vogel, Alexander, Schwarze, Benedikt, Seufert, Florian, Licha, Kai, Wycisk, Virginia, Kilian, Wolfgang, Hildebrand, Peter W., Mitschang, Lorenz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9919357/
https://www.ncbi.nlm.nih.gov/pubmed/36771089
http://dx.doi.org/10.3390/molecules28031424