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Towards Probing Conformational States of Y2 Receptor Using Hyperpolarized (129)Xe NMR
G protein-coupled receptors can adopt many different conformational states, each of them exhibiting different restraints towards downstream signaling pathways. One promising strategy to identify and quantify this conformational landscape is to introduce a cysteine at a receptor site sensitive to dif...
Autores principales: | Schmidt, Peter, Vogel, Alexander, Schwarze, Benedikt, Seufert, Florian, Licha, Kai, Wycisk, Virginia, Kilian, Wolfgang, Hildebrand, Peter W., Mitschang, Lorenz |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9919357/ https://www.ncbi.nlm.nih.gov/pubmed/36771089 http://dx.doi.org/10.3390/molecules28031424 |
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