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Rare Missense Variants of the Human β4 Subunit Alter Nicotinic α3β4 Receptor Plasma Membrane Localisation

α3β4 nicotinic acetylcholine receptors (nARs) are pentameric ligand-gated cation channels that function in peripheral tissue and in the peripheral and central nervous systems, where they are critical mediators of ganglionic synaptic transmission and modulators of reward-related behaviours. In the pe...

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Detalles Bibliográficos
Autores principales: Colombo, Sara Francesca, Galli, Cecilia, Crespi, Arianna, Renzi, Massimiliano, Gotti, Cecilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9919425/
https://www.ncbi.nlm.nih.gov/pubmed/36770914
http://dx.doi.org/10.3390/molecules28031247