Synthesis and Biological Evaluation of Novel Dispiro-Indolinones with Anticancer Activity

Novel variously substituted thiohydantoin-based dispiro-indolinones were prepared using a regio- and diastereoselective synthetic route from 5-arylidene-2-thiohydantoins, isatines, and sarcosine. The obtained molecules were subsequently evaluated in vitro against the cancer cell lines LNCaP, PC3, HC...

Descripción completa

Detalles Bibliográficos
Autores principales: Ivanenkov, Yan A., Kukushkin, Maxim E., Beloglazkina, Anastasia A., Shafikov, Radik R., Barashkin, Alexander A., Ayginin, Andrey A., Serebryakova, Marina S., Majouga, Alexander G., Skvortsov, Dmitry A., Tafeenko, Viktor A., Beloglazkina, Elena K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9919490/
https://www.ncbi.nlm.nih.gov/pubmed/36770991
http://dx.doi.org/10.3390/molecules28031325

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9919490/
https://www.ncbi.nlm.nih.gov/pubmed/36770991
http://dx.doi.org/10.3390/molecules28031325

Ejemplares similares