Generation of Aurachin Derivatives by Whole-Cell Biotransformation and Evaluation of Their Antiprotozoal Properties

The natural product aurachin D is a farnesylated quinolone alkaloid, which is known to possess activity against the causative agent of malaria, Plasmodium spp. In this study, we show that aurachin D inhibits other parasitic protozoa as well. While aurachin D had only a modest effect on Trypanosoma b...

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Detalles Bibliográficos
Autores principales: Kruth, Sebastian, Zimmermann, Cindy J.-M., Kuhr, Katharina, Hiller, Wolf, Lütz, Stephan, Pietruszka, Jörg, Kaiser, Marcel, Nett, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9919615/
https://www.ncbi.nlm.nih.gov/pubmed/36770729
http://dx.doi.org/10.3390/molecules28031066

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9919615/
https://www.ncbi.nlm.nih.gov/pubmed/36770729
http://dx.doi.org/10.3390/molecules28031066

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