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Generation of Aurachin Derivatives by Whole-Cell Biotransformation and Evaluation of Their Antiprotozoal Properties
The natural product aurachin D is a farnesylated quinolone alkaloid, which is known to possess activity against the causative agent of malaria, Plasmodium spp. In this study, we show that aurachin D inhibits other parasitic protozoa as well. While aurachin D had only a modest effect on Trypanosoma b...
Autores principales: | Kruth, Sebastian, Zimmermann, Cindy J.-M., Kuhr, Katharina, Hiller, Wolf, Lütz, Stephan, Pietruszka, Jörg, Kaiser, Marcel, Nett, Markus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9919615/ https://www.ncbi.nlm.nih.gov/pubmed/36770729 http://dx.doi.org/10.3390/molecules28031066 |
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