A Versatile Continuous Fluorometric Enzymatic Assay for Targeting Nicotinate Phosphoribosyltransferase

The maintenance of a proper NAD(+) pool is essential for cell survival, and tumor cells are particularly sensitive to changes in coenzyme levels. In this view, the inhibition of NAD(+) biosynthesis is considered a promising therapeutic approach. Current research is mostly focused on targeting the en...

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Detalles Bibliográficos
Autores principales: Minazzato, Gabriele, Marangoni, Elisa, Fortunato, Carlo, Petrelli, Riccardo, Cappellacci, Loredana, Del Bello, Fabio, Sorci, Leonardo, Gasparrini, Massimiliano, Piacente, Francesco, Bruzzone, Santina, Raffaelli, Nadia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9919730/
https://www.ncbi.nlm.nih.gov/pubmed/36770640
http://dx.doi.org/10.3390/molecules28030961

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9919730/
https://www.ncbi.nlm.nih.gov/pubmed/36770640
http://dx.doi.org/10.3390/molecules28030961

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