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A Versatile Continuous Fluorometric Enzymatic Assay for Targeting Nicotinate Phosphoribosyltransferase
The maintenance of a proper NAD(+) pool is essential for cell survival, and tumor cells are particularly sensitive to changes in coenzyme levels. In this view, the inhibition of NAD(+) biosynthesis is considered a promising therapeutic approach. Current research is mostly focused on targeting the en...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9919730/ https://www.ncbi.nlm.nih.gov/pubmed/36770640 http://dx.doi.org/10.3390/molecules28030961 |