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Drugging the Undruggable Trypanosoma brucei Monothiol Glutaredoxin 1

Trypanosoma brucei is a species of kinetoplastid causing sleeping sickness in humans and nagana in cows and horses. One of the peculiarities of this species of parasites is represented by their redox metabolism. One of the proteins involved in this redox machinery is the monothiol glutaredoxin 1 (1C...

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Detalles Bibliográficos
Autores principales: Favaro, Annagiulia, Bolcato, Giovanni, Comini, Marcelo A., Moro, Stefano, Bellanda, Massimo, Sturlese, Mattia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9919793/
https://www.ncbi.nlm.nih.gov/pubmed/36770941
http://dx.doi.org/10.3390/molecules28031276