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Design, Synthesis and Structure-Activity Relationship Studies of Nicotinamide Derivatives as Potent Antifungal Agents by Disrupting Cell Wall

Fungal infections pose a serious challenge to human health due to the limited paucity of antifungal treatments. Starting as a hit compound screened from our compound library, a series of nicotinamide derivatives have been successfully synthesized via a facile one-step coupling reaction of aromatic c...

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Detalles Bibliográficos
Autores principales: Ni, Tingjunhong, Xie, Fei, Li, Liping, Hao, Yumeng, Chi, Xiaochen, Yan, Lan, Zhang, Dazhi, Jiang, Yuanying, Lv, Quanzhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9919825/
https://www.ncbi.nlm.nih.gov/pubmed/36770802
http://dx.doi.org/10.3390/molecules28031135