Unexpected Decarbonylation of Acylethynylpyrroles under the Action of Cyanomethyl Carbanion: A Robust Access to Ethynylpyrroles

It has been found that the addition of CH(2)CN(−) anion to the carbonyl group of acylethynylpyrroles, generated from acetonitrile and t-BuOK, results in the formation of acetylenic alcohols, which undergo unexpectedly easy (room temperature) decomposition to ethynylpyrroles and cyanomethylphenylketo...

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Detalles Bibliográficos
Autores principales: Tomilin, Denis N., Sobenina, Lyubov N., Belogolova, Alexandra M., Trofimov, Alexander B., Ushakov, Igor A., Trofimov, Boris A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9919934/
https://www.ncbi.nlm.nih.gov/pubmed/36771055
http://dx.doi.org/10.3390/molecules28031389

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9919934/
https://www.ncbi.nlm.nih.gov/pubmed/36771055
http://dx.doi.org/10.3390/molecules28031389

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