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Evaluation of Hold-Up Volume Determination Methods and Markers in Hydrophilic Interaction Liquid Chromatography

Common methods for hold-up time and volume determination in Reversed-Phase Liquid Chromatography (RPLC) have been tested for Hydrophilic Interaction Liquid Chromatography (HILIC). A zwitterionic ZIC-HILIC column has been used for the testing. The pycnometric determination method, based on difference...

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Detalles Bibliográficos
Autores principales: Redón, Lídia, Subirats, Xavier, Rosés, Martí
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9920175/
https://www.ncbi.nlm.nih.gov/pubmed/36771038
http://dx.doi.org/10.3390/molecules28031372