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Mesoporous Silica Nanoparticles Coated with Carboxymethyl Chitosan for 5-Fluorouracil Ocular Delivery: Characterization, In Vitro and In Vivo Studies

This study investigates the development of topically applied non-invasive amino-functionalized silica nanoparticles (AMSN) and O-Carboxymethyl chitosan-coated AMSN (AMSN-CMC) for ocular delivery of 5-Fluorouracil (5-FU). Particle characterization was performed by the DLS technique (Zeta-Sizer), and...

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Detalles Bibliográficos
Autores principales: Alhowyan, Adel Ali, Kalam, Mohd Abul, Iqbal, Muzaffar, Raish, Mohammad, El-Toni, Ahmed M., Alkholief, Musaed, Almomen, Aliyah A., Alshamsan, Aws
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9920178/
https://www.ncbi.nlm.nih.gov/pubmed/36770926
http://dx.doi.org/10.3390/molecules28031260