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Mesoporous Silica Nanoparticles Coated with Carboxymethyl Chitosan for 5-Fluorouracil Ocular Delivery: Characterization, In Vitro and In Vivo Studies
This study investigates the development of topically applied non-invasive amino-functionalized silica nanoparticles (AMSN) and O-Carboxymethyl chitosan-coated AMSN (AMSN-CMC) for ocular delivery of 5-Fluorouracil (5-FU). Particle characterization was performed by the DLS technique (Zeta-Sizer), and...
Autores principales: | Alhowyan, Adel Ali, Kalam, Mohd Abul, Iqbal, Muzaffar, Raish, Mohammad, El-Toni, Ahmed M., Alkholief, Musaed, Almomen, Aliyah A., Alshamsan, Aws |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9920178/ https://www.ncbi.nlm.nih.gov/pubmed/36770926 http://dx.doi.org/10.3390/molecules28031260 |
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