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Direct Regioselective C-H Cyanation of Purines

A direct regioselective C-H cyanation of purines was developed through a sequential triflic anhydride activation, nucleophilic cyanation with TMSCN, followed by a process of base-mediated elimination of triflous acid (CF(3)SO(2)H). In most cases, the direct C-H cyanation occurred on the electron-ric...

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Detalles Bibliográficos
Autores principales: Li, Luyong, Hu, Jie, Fu, Yuqing, Shi, Xiaolin, Du, Hongguang, Xu, Jiaxi, Chen, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9920237/
https://www.ncbi.nlm.nih.gov/pubmed/36770582
http://dx.doi.org/10.3390/molecules28030914