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Biotransformation of Penindolone, an Influenza A Virus Inhibitor

Penindolone (PND) is a novel broad-spectrum anti-Influenza A Virus (IAV) agent blocking hemagglutinin-mediated adsorption and membrane fusion. The goal of this work was to reveal the metabolic route of PND in rats. Ultra-high-performance liquid chromatography tandem high-resolution mass spectrometry...

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Detalles Bibliográficos
Autores principales: Liu, Shuai, Zheng, Keming, Jiang, Yilin, Gai, Susu, Li, Bohan, Li, Dehai, Yang, Shuang, Lv, Zhihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9920254/
https://www.ncbi.nlm.nih.gov/pubmed/36771146
http://dx.doi.org/10.3390/molecules28031479