Chemical Modification of Auranofin Yields a New Family of Anticancer Drug Candidates: The Gold(I) Phosphite Analogues

A panel of four novel gold(I) complexes, inspired by the clinically established gold drug auranofin (1-Thio-β-D-glucopyranosatotriethylphosphine gold-2,3,4,6-tetraacetate), was prepared and characterized. All these compounds feature the replacement of the triethylphosphine ligand of the parent compo...

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Detalles Bibliográficos
Autores principales: Cirri, Damiano, Geri, Andrea, Massai, Lara, Mannelli, Michele, Gamberi, Tania, Magherini, Francesca, Becatti, Matteo, Gabbiani, Chiara, Pratesi, Alessandro, Messori, Luigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9920260/
https://www.ncbi.nlm.nih.gov/pubmed/36770719
http://dx.doi.org/10.3390/molecules28031050

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9920260/
https://www.ncbi.nlm.nih.gov/pubmed/36770719
http://dx.doi.org/10.3390/molecules28031050

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