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New Bicyclic Pyridine-Based Hybrids Linked to the 1,2,3-Triazole Unit: Synthesis via Click Reaction and Evaluation of Neurotropic Activity and Molecular Docking

The synthesis of new original bicyclic pyridine-based hybrids linked to the 1,2,3-triazole unit was described via a click reaction. The anticonvulsant activity and some psychotropic properties of the new compounds were evaluated. The biological assays demonstrated that some of the studied compounds...

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Detalles Bibliográficos
Autores principales: Sirakanyan, Samvel N., Spinelli, Domenico, Petrou, Anthi, Geronikaki, Athina, Kartsev, Victor G., Hakobyan, Elmira K., Yegoryan, Hasmik A., Zuppiroli, Luca, Zuppiroli, Riccardo, Ayvazyan, Armen G., Paronikyan, Ruzanna G., Arakelyan, Tatevik A., Hovakimyan, Anush A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9920413/
https://www.ncbi.nlm.nih.gov/pubmed/36770592
http://dx.doi.org/10.3390/molecules28030921