Design, Synthesis and Biological Evaluation of Conjugates of 3-O-Descladinose-azithromycin and Nucleobases against rRNA A2058G- or A2059G-Mutated Strains

Structurally unrelated antibiotics MLS(B) (macrolide-lincosamide-streptogramin B) compromised with clinically resistant pathogens because of the cross-resistance resulting from the structural modification of rRNA A2058. The structure–activity relationships of a novel 3-O-descladinose azithromycin ch...

Descripción completa

Detalles Bibliográficos
Autores principales: Lian, Xiaotian, Liu, Wentian, Fan, Bingzhi, Yu, Mingjia, Liang, Jianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9920417/
https://www.ncbi.nlm.nih.gov/pubmed/36770992
http://dx.doi.org/10.3390/molecules28031327

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9920417/
https://www.ncbi.nlm.nih.gov/pubmed/36770992
http://dx.doi.org/10.3390/molecules28031327

Ejemplares similares