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The Structural Basis of African Swine Fever Virus pS273R Protease Binding to E64 through Molecular Dynamics Simulations

Identification of novel drugs for anti-African swine fever (ASF) applications is of utmost urgency, as it negatively affects pig farming and no effective vaccine or treatment is currently available. African swine fever virus (ASFV) encoded pS273R is a cysteine protease that plays an important role i...

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Detalles Bibliográficos
Autores principales: Lu, Gen, Ou, Kang, Jing, Yiwen, Zhang, Huan, Feng, Shouhua, Yang, Zuofeng, Shen, Guoshun, Liu, Jinling, Wu, Changde, Wei, Shu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9920524/
https://www.ncbi.nlm.nih.gov/pubmed/36771101
http://dx.doi.org/10.3390/molecules28031435