Discovery of Bis-Imidazoline Derivatives as New CXCR4 Ligands

The chemokine receptor CXCR4 and its ligand CXCL12 regulate leukocyte trafficking, homeostasis and functions and are potential therapeutic targets in many diseases such as HIV-1 infection and cancers. Here, we identified new CXCR4 ligands in the CERMN chemical library using a FRET-based high-through...

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Detalles Bibliográficos
Autores principales: Zhou, Zhicheng, Staropoli, Isabelle, Brelot, Anne, Suzanne, Peggy, Lesnard, Aurélien, Fontaine, Fanny, Perato, Serge, Rault, Sylvain, Helynck, Olivier, Arenzana-Seisdedos, Fernando, Sopkova-de Oliveira Santos, Jana, Lagane, Bernard, Munier-Lehmann, Hélène, Colin, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9920567/
https://www.ncbi.nlm.nih.gov/pubmed/36770826
http://dx.doi.org/10.3390/molecules28031156

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9920567/
https://www.ncbi.nlm.nih.gov/pubmed/36770826
http://dx.doi.org/10.3390/molecules28031156

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