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Discovery of Bis-Imidazoline Derivatives as New CXCR4 Ligands
The chemokine receptor CXCR4 and its ligand CXCL12 regulate leukocyte trafficking, homeostasis and functions and are potential therapeutic targets in many diseases such as HIV-1 infection and cancers. Here, we identified new CXCR4 ligands in the CERMN chemical library using a FRET-based high-through...
Autores principales: | Zhou, Zhicheng, Staropoli, Isabelle, Brelot, Anne, Suzanne, Peggy, Lesnard, Aurélien, Fontaine, Fanny, Perato, Serge, Rault, Sylvain, Helynck, Olivier, Arenzana-Seisdedos, Fernando, Sopkova-de Oliveira Santos, Jana, Lagane, Bernard, Munier-Lehmann, Hélène, Colin, Philippe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9920567/ https://www.ncbi.nlm.nih.gov/pubmed/36770826 http://dx.doi.org/10.3390/molecules28031156 |
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