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Approved Small-Molecule ATP-Competitive Kinases Drugs Containing Indole/Azaindole/Oxindole Scaffolds: R&D and Binding Patterns Profiling

Kinases are among the most important families of biomolecules and play an essential role in the regulation of cell proliferation, apoptosis, metabolism, and other critical physiological processes. The dysregulation and gene mutation of kinases are linked to the occurrence and development of various...

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Detalles Bibliográficos
Autores principales: Zhang, Haofan, He, Fengming, Gao, Guiping, Lu, Sheng, Wei, Qiaochu, Hu, Hongyu, Wu, Zhen, Fang, Meijuan, Wang, Xiumin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9920796/
https://www.ncbi.nlm.nih.gov/pubmed/36770611
http://dx.doi.org/10.3390/molecules28030943