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Development of Polymersomes Co-Delivering Doxorubicin and Melittin to Overcome Multidrug Resistance

Multidrug resistance (MDR) is one of the major barriers in chemotherapy. It is often related to the overexpression of efflux receptors such as P-glycoprotein (P-gp). Overexpressed efflux receptors inhibit chemotherapeutic efficacy by pumping out intracellularly delivered anticancer drugs. In P-gp-me...

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Detalles Bibliográficos
Autores principales: Han, Eunkyung, Kim, Doyeon, Cho, Youngheun, Lee, Seonock, Kim, Jungho, Kim, Hyuncheol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9920864/
https://www.ncbi.nlm.nih.gov/pubmed/36770754
http://dx.doi.org/10.3390/molecules28031087