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Parity is associated with long-term differences in DNA methylation at genes related to neural plasticity in multiple sclerosis

BACKGROUND: Pregnancy in women with multiple sclerosis (wwMS) is associated with a reduction of long-term disability progression. The mechanism that drives this effect is unknown, but converging evidence suggests a role for epigenetic mechanisms altering immune and/or central nervous system function...

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Detalles Bibliográficos
Autores principales: Campagna, Maria Pia, Xavier, Alexandre, Stankovich, Jim, Maltby, Vicki E., Slee, Mark, Yeh, Wei Z., Kilpatrick, Trevor, Scott, Rodney J., Butzkueven, Helmut, Lechner-Scott, Jeannette, Lea, Rodney A., Jokubaitis, Vilija G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9921068/
https://www.ncbi.nlm.nih.gov/pubmed/36765422
http://dx.doi.org/10.1186/s13148-023-01438-4