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BAX as the mediator of C-MYC sensitizes acute lymphoblastic leukemia to TLR9 agonists
BACKGROUND: The prognosis of B-cell acute lymphoblastic leukemia (B-ALL) has improved significantly with current first-line therapy, although the recurrence of B-ALL is still a problem. Toll-like receptor 9 (TLR9) agonists have shown good safety and efficiency as immune adjuvants. Apart from their i...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9921080/ https://www.ncbi.nlm.nih.gov/pubmed/36765389 http://dx.doi.org/10.1186/s12967-023-03969-z |