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Dual-specificity phosphatases 22-deficient T cells contribute to the pathogenesis of ankylosing spondylitis

BACKGROUND: Dual-specificity phosphatases (DUSPs) can dephosphorylate both tyrosine and serine/threonine residues of their substrates and regulate T cell-mediated immunity and autoimmunity. The aim of this study was to investigate the potential roles of DUSPs in ankylosing spondylitis (AS). METHODS:...

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Detalles Bibliográficos
Autores principales: Chen, Ming-Han, Chuang, Huai-Chia, Yeh, Yi-Chen, Chou, Chung-Tei, Tan, Tse-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9921195/
https://www.ncbi.nlm.nih.gov/pubmed/36765305
http://dx.doi.org/10.1186/s12916-023-02745-6