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Systemic proinflammatory−profibrotic response in aortic stenosis patients with diabetes and its relationship with myocardial remodeling and clinical outcome

BACKGROUND: Previous studies have mainly focused more on how diabetes affects the valve than the myocardium in aortic stenosis (AS). In the pressure-overloaded heart, myocardial fibrosis is an important driver of the progression from compensated hypertrophy to heart failure. Using comprehensive noni...

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Detalles Bibliográficos
Autores principales: Lee, Hyun-Jung, Park, Chan Soon, Lee, Sahmin, Park, Jun-Bean, Kim, Hyung-Kwan, Park, Sung-Ji, Kim, Yong-Jin, Lee, Seung-Pyo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9921197/
https://www.ncbi.nlm.nih.gov/pubmed/36765354
http://dx.doi.org/10.1186/s12933-023-01763-1