In Silico Targeting of Fascin Protein for Cancer Therapy: Benchmarking, Virtual Screening and Molecular Dynamics Approaches

Fascin is an actin-bundling protein overexpressed in various invasive metastatic carcinomas through promoting cell migration and invasion. Therefore, blocking Fascin binding sites is considered a vital target for antimetastatic drugs. This inspired us to find new Fascin binding site blockers. First,...

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Detalles Bibliográficos
Autores principales: Hassan, Heba H. A., Ismail, Muhammad I., Abourehab, Mohammed A. S., Boeckler, Frank M., Ibrahim, Tamer M., Arafa, Reem K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9921211/
https://www.ncbi.nlm.nih.gov/pubmed/36770963
http://dx.doi.org/10.3390/molecules28031296

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9921211/
https://www.ncbi.nlm.nih.gov/pubmed/36770963
http://dx.doi.org/10.3390/molecules28031296

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