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Does the likelihood of malignancy in thyroid nodules with RAS mutations increase in direct proportion with the allele frequency percentage?

BACKGROUND: Genomic testing has enhanced pre-surgical decision making for cytologically indeterminate thyroid nodules, but there remains uncertainty regarding RAS mutations. The addition of extra genetic alterations to previous driver mutation panels has been shown to improve predictive value. This...

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Detalles Bibliográficos
Autores principales: Hudson, Thomas J., Pusztaszeri, Marc Philippe, Hier, Michael P., Forest, Veronique-Isabelle, Yang, Ji-Wei, Payne, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9921308/
https://www.ncbi.nlm.nih.gov/pubmed/36774522
http://dx.doi.org/10.1186/s40463-022-00611-8