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A transdermal treatment with MC903 ameliorates diet-induced obesity by reducing visceral fat and increasing myofiber thickness and energy consumption in mice

AIM: MC903 is a synthetic derivative of vitamin D3 that has been designed to diminish its impact on calcium metabolism and is clinically used as a transdermal reagent for psoriasis. Animal studies showed that an oral or intraperitoneal vitamin D3 treatment prevented the development of obesity. In co...

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Detalles Bibliográficos
Autores principales: Wada, Tsutomu, Miyazawa, Yuichiro, Ikurumi, Misa, Fuse, Kento, Okekawa, Akira, Onogi, Yasuhiro, Saito, Shigeru, Tsuneki, Hiroshi, Sasaoka, Toshiyasu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9921322/
https://www.ncbi.nlm.nih.gov/pubmed/36774476
http://dx.doi.org/10.1186/s12986-023-00732-5