Tailoring of Novel Bile Salt Stabilized Vesicles for Enhanced Transdermal Delivery of Simvastatin: A New Therapeutic Approach against Inflammation

Simvastatin (SMV), a cholesterol-lowering agent, has antioxidant and anti-inflammatory effects. Nevertheless, the oral use of SMV is linked with poor systemic bioavailability owing to its limited aqueous solubility and extensive first-pass metabolism. The aim of this study was to evaluate the feasib...

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Detalles Bibliográficos
Autores principales: Khafagy, El-Sayed, Almutairy, Bjad K., Abu Lila, Amr Selim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9921379/
https://www.ncbi.nlm.nih.gov/pubmed/36771977
http://dx.doi.org/10.3390/polym15030677

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9921379/
https://www.ncbi.nlm.nih.gov/pubmed/36771977
http://dx.doi.org/10.3390/polym15030677

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