Design and Synthesis of New Modified Flexible Purine Bases as Potential Inhibitors of Human PNP

The great interest in studying the structure of human purine nucleoside phosphorylase (hPNP) and the continued search for effective inhibitors is due to the importance of the enzyme as a target in the therapy of T-cell proliferative diseases. In addition, hPNP inhibitors are used in organ transplant...

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Detalles Bibliográficos
Autores principales: Khandazhinskaya, Anastasia, Fateev, Ilja, Eletskaya, Barbara, Maslova, Anna, Konstantinova, Irina, Seley-Radtke, Katherine, Kochetkov, Sergey, Matyugina, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9921493/
https://www.ncbi.nlm.nih.gov/pubmed/36770593
http://dx.doi.org/10.3390/molecules28030928

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9921493/
https://www.ncbi.nlm.nih.gov/pubmed/36770593
http://dx.doi.org/10.3390/molecules28030928

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