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Design and Synthesis of New Modified Flexible Purine Bases as Potential Inhibitors of Human PNP
The great interest in studying the structure of human purine nucleoside phosphorylase (hPNP) and the continued search for effective inhibitors is due to the importance of the enzyme as a target in the therapy of T-cell proliferative diseases. In addition, hPNP inhibitors are used in organ transplant...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9921493/ https://www.ncbi.nlm.nih.gov/pubmed/36770593 http://dx.doi.org/10.3390/molecules28030928 |