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Spermatogenesis associated serine rich 2 like plays a prognostic factor and therapeutic target in acute myeloid leukemia by regulating the JAK2/STAT3/STAT5 axis

BACKGROUND: Spermatogenesis associated serine rich 2 like (SPATS2L) was highly expressed in homoharringtonine (HHT) resistant acute myeloid leukemia (AML) cell lines. However, its role is little known in AML. The present study aimed to investigate the function of SPATS2L in AML pathogenesis and eluc...

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Detalles Bibliográficos
Autores principales: Li, Fenglin, Ye, Wenle, Yao, Yiyi, Wei, Wenwen, Lin, Xiangjie, Zhuang, Haihui, Li, Chenying, Li, Xia, Ling, Qing, Hu, Chao, Huang, Xin, Qian, Yu, Mao, Shihui, Huang, Jiansong, Lu, Ying, Jin, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9921581/
https://www.ncbi.nlm.nih.gov/pubmed/36774517
http://dx.doi.org/10.1186/s12967-023-03968-0