Conformational Dynamics and Stability of Bilayers Formed by Mycolic Acids from the Mycobacterium tuberculosis Outer Membrane

Bilayers of mycolic acids (MAs) form the outer membrane of Mycobacterium tuberculosis that has high strength and extremely low permeability for external molecules (including antibiotics). For the first time, we were able to study them using the all-atom long-term molecular dynamic simulations (from...

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Detalles Bibliográficos
Autores principales: Savintseva, Liana A., Steshin, Ilya S., Avdoshin, Alexander A., Panteleev, Sergey V., Rozhkov, Alexey V., Shirokova, Ekaterina A., Livshits, Grigory D., Vasyankin, Alexander V., Radchenko, Eugene V., Ignatov, Stanislav K., Palyulin, Vladimir A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9921641/
https://www.ncbi.nlm.nih.gov/pubmed/36771014
http://dx.doi.org/10.3390/molecules28031347

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9921641/
https://www.ncbi.nlm.nih.gov/pubmed/36771014
http://dx.doi.org/10.3390/molecules28031347

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