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The Genetic Background Is Shaping Cecal Enlargement in the Absence of Intestinal Microbiota

Germ-free (GF) rodents have become a valuable tool for studying the role of intestinal microbes on the host physiology. The major characteristic of GF rodents is an enlarged cecum. The accumulation of mucopolysaccharides, digestion enzymes and water in the intestinal lumen drives this phenotype. Mic...

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Detalles Bibliográficos
Autores principales: Bolsega, Silvia, Smoczek, Anna, Meng, Chen, Kleigrewe, Karin, Scheele, Tim, Meller, Sebastian, Glage, Silke, Volk, Holger A., Bleich, André, Basic, Marijana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9921660/
https://www.ncbi.nlm.nih.gov/pubmed/36771343
http://dx.doi.org/10.3390/nu15030636