Cargando…

eEF2K Inhibitor Design: The Progression of Exemplary Structure-Based Drug Design

The α-kinase, eEF2K, phosphorylates the threonine 56 residue of eEF2 to inhibit global peptide elongation (protein translation). As a master regulator of protein synthesis, in combination with its unique atypical kinase active site, investigations into the targeting of eEF2K represents a case of int...

Descripción completa

Detalles Bibliográficos
Autores principales: Klupt, Kody A., Jia, Zongchao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9921739/
https://www.ncbi.nlm.nih.gov/pubmed/36770760
http://dx.doi.org/10.3390/molecules28031095