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eEF2K Inhibitor Design: The Progression of Exemplary Structure-Based Drug Design
The α-kinase, eEF2K, phosphorylates the threonine 56 residue of eEF2 to inhibit global peptide elongation (protein translation). As a master regulator of protein synthesis, in combination with its unique atypical kinase active site, investigations into the targeting of eEF2K represents a case of int...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9921739/ https://www.ncbi.nlm.nih.gov/pubmed/36770760 http://dx.doi.org/10.3390/molecules28031095 |