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Inhibition of Klf10 Attenuates Oxidative Stress-Induced Senescence of Chondrocytes via Modulating Mitophagy

Osteoarthritis (OA) is the most prevalent degenerative joint disease in the elderly. Accumulation of evidence has suggested that chondrocyte senescence plays a significant role in OA development. Here, we show that Krüppel-like factor 10 (Klf10), also named TGFβ inducible early gene-1 (TIEG1), is in...

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Detalles Bibliográficos
Autores principales: Shang, Jie, Lin, Nan, Peng, Rong, Jiang, Ning, Wu, Biao, Xing, Baizhou, Lin, Shiyuan, Xu, Xianghe, Lu, Huading
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9921806/
https://www.ncbi.nlm.nih.gov/pubmed/36770589
http://dx.doi.org/10.3390/molecules28030924