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Myeloid dendritic cells are increased in the lesional skin and associated with pruritus in patients with prurigo nodularis
The number of dermal mDCs (CD11c(+) cells) was increased with itch intensity (r = 0.886, p = 0.003) using immunofluorescence (IF). On IF, CD11c(+) mDCs expressed IL‐31 in lesional PN skin. Fluorescence in situ hybridization combined with IF also confirmed IL‐31 mRNA expression by mDCs in PN lesion....
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9921813/ https://www.ncbi.nlm.nih.gov/pubmed/36789100 http://dx.doi.org/10.1002/mco2.204 |