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Synthesis and Preclinical Evaluation of Three Novel (68)Ga-Labeled Bispecific PSMA/FAP-Targeting Tracers for Prostate Cancer Imaging

Tumor heterogeneity limits the efficacy and reliability of monospecific radiopharmaceuticals in prostate cancer diagnosis and therapy. To overcome this limitation and improve lesion detection sensitivity, we developed and evaluated three bispecific radiotracers that can target both prostate-specific...

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Detalles Bibliográficos
Autores principales: Verena, Arsyangela, Zhang, Zhengxing, Kuo, Hsiou-Ting, Merkens, Helen, Zeisler, Jutta, Wilson, Ryan, Bendre, Shreya, Wong, Antonio A. W. L., Bénard, François, Lin, Kuo-Shyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9921851/
https://www.ncbi.nlm.nih.gov/pubmed/36770755
http://dx.doi.org/10.3390/molecules28031088