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Roles of G4-DNA and G4-RNA in Class Switch Recombination and Additional Regulations in B-Lymphocytes

Mature B cells notably diversify immunoglobulin (Ig) production through class switch recombination (CSR), allowing the junction of distant “switch” (S) regions. CSR is initiated by activation-induced deaminase (AID), which targets cytosines adequately exposed within single-stranded DNA of transcribe...

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Detalles Bibliográficos
Autores principales: Dézé, Ophélie, Laffleur, Brice, Cogné, Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9921937/
https://www.ncbi.nlm.nih.gov/pubmed/36770824
http://dx.doi.org/10.3390/molecules28031159